
Charles Edmund Cullen is widely considered one of the most prolific serial killers in American history. Working as a registered nurse across nine hospitals and one nursing home in New Jersey and Pennsylvania over 16 years, he murdered at least 29 patients – though investigators believe his true victim count may approach 400, which would make him the deadliest serial killer ever documented in the United States.
| Detail | Information |
|---|---|
| Full Name | Charles Edmund Cullen |
| Born | February 22, 1960, West Orange, New Jersey |
| Aliases | “Angel of Death,” “Satan’s Son,” “Killer Nurse” |
| Occupation | Registered Nurse |
| Active Period | 1988–2003 (16 years) |
| Confirmed Victims | 29 murders, 6 attempted murders |
| Estimated Victims | 40 (self-claimed) to 400 (investigator estimates) |
| Method | Lethal drug overdoses (primarily digoxin, insulin) |
| Current Status | Incarcerated at New Jersey State Prison, serving 11 consecutive life sentences; earliest parole date: June 10, 2388 |
Cullen’s childhood was marked by profound tragedy, loss, and isolation that likely shaped his psychological development.
Family Losses: Born as the youngest of eight children in a deeply religious Catholic family, Cullen was only seven months old when his father, a bus driver, died at age 56. His mother, the only person he claimed showed him affection, was killed in a car accident when he was 17 years old. Two of his siblings also died during his lifetime, including his brother James from a drug overdose in 1987 and his brother Edmond from brain cancer in 2001.
First Suicide Attempt at Age 9: At just nine years old, Cullen attempted to take his own life by mixing chemicals from a chemistry set and drinking the concoction – the first of approximately 20 suicide attempts throughout his life. By his own admission, his childhood was “miserable,” feeling like “a mistake, an unwanted and unplanned addition” to a family already struggling financially.
Social Isolation and Bullying: Cullen was teased relentlessly at school and had few friends. At age 11, he co-wrote a book with one of his only friends entitled Infinity Years Will Never Know about growing up in a world where “life was meaningless.” As a teenager, he became fascinated with Dostoyevsky’s works, particularly Crime and Punishment, a novel about a man who commits murder.
Early Signs of Violence: When bullies tormented him at a high school party, Cullen retaliated by spiking their drinks with rat poison. Fortunately, no one died from this incident. This early act of poisoning would foreshadow his later method of killing.
After dropping out of high school following his mother’s death in April 1978, Cullen enlisted in the U.S. Navy and was trained as a ballistic missiles technician, eventually serving aboard the nuclear submarine USS Woodrow Wilson.
Continued Harassment: The bullying that plagued him in school followed him into military service. Fellow crew members considered him a “misfit” and taunted him with the nickname “Fish-Belly” due to his pale, sallow complexion.
Disturbing Behavior: In 1980, Cullen was discovered sitting at the missile control panel wearing a stolen hospital gown, surgical mask, and latex gloves – an incident that was reported and led to his reassignment to the USS Canopus. He continued making suicide attempts, with his final attempt leading to his discharge from the Navy in March 1984. Naval records have not publicly confirmed whether the discharge was for medical or psychological reasons.
Upon leaving the Navy, Cullen enrolled at Mountainside Hospital School of Nursing in Montclair, New Jersey, graduating in 1987. That same year, he married computer programmer Adrienne Taub, and the couple eventually had two daughters.
| Hospital/Facility | Location | Period | Confirmed Victims | Notes |
|---|---|---|---|---|
| St. Barnabas Medical Center | Livingston, NJ | 1987–1992 | 11+ | First murder June 1988; left during IV tampering investigation |
| Warren Hospital | Phillipsburg, NJ | 1992–1993 | 3 | Killed 3 elderly women; passed polygraph during investigation |
| Hunterdon Medical Center | Flemington, NJ | 1994–1996 | 5 | Received award for “diligence and hard work” before murders |
| Morristown Memorial Hospital | Morristown, NJ | 1996–1997 | Unknown | Fired for poor job performance |
| Liberty Nursing & Rehab Center | Allentown, PA | 1998 | 0 | Fired after being seen entering patient room with syringes |
| Easton Hospital | Easton, PA | 1998–1999 | 1 | Coroner found lethal digoxin but investigation inconclusive |
| Lehigh Valley Hospital | Salisbury Township, PA | 1999–2000 | 1 (1 attempted) | Murdered 22-year-old burn victim Matthew Mattern |
| St. Luke’s Hospital | Bethlehem, PA | 2000–2002 | 5 (2 attempted) | Nurses reported suspicions to police; investigation dropped |
| Sacred Heart Hospital | Allentown, PA | 2002 | 0 | Left after rumors circulated about him |
| Somerset Medical Center | Somerville, NJ | 2002–2003 | 13 (3 attempted) | Final workplace; caught through computer tracking |
Cullen developed a sophisticated understanding of hospital systems that allowed him to murder patients while evading detection for over a decade and a half.
Primary Weapon – Digoxin: His drug of choice was digoxin, a cardiac medication used to treat irregular heartbeats and heart failure. In high doses, digoxin causes fatal cardiac arrhythmias and is difficult to detect in routine autopsies. Cullen would access the drug through automated drug-dispensing cabinets called Pyxis systems by logging in under medications like Tylenol stored in the same drawer, thereby avoiding any record of withdrawing digoxin.
Other Medications Used: Beyond digoxin, Cullen employed insulin, lidocaine, norepinephrine, dobutamine, sodium nitroprusside, epinephrine, and Pavulon to kill patients. Some victims survived initial overdose attempts, leading Cullen to try repeatedly or switch medications to “finish the job.”
IV Bag Contamination: Cullen often injected lethal substances into patients’ intravenous fluid bags, meaning deaths did not always occur when he was present – making it harder to connect him to the crimes.
The following 29 victims have been officially confirmed through Cullen’s guilty pleas and forensic evidence:
| Name | Age | Hospital | Date of Death |
|---|---|---|---|
| John W. Yengo Sr. | 72 | St. Barnabas | June 11, 1988 |
| Lucy Mugavero | 90 | Warren | March 9, 1993 |
| Mary Natoli | 85 | Warren | July 23, 1993 |
| Helen Dean | 91 | Warren | September 1, 1993 |
| LeRoy Sinn | 71 | Hunterdon | January 21, 1996 |
| Earl Young | 76 | Hunterdon | May 31, 1996 |
| Catherine Dext | 49 | Hunterdon | June 9, 1996 |
| Frank Mazzacco | 66 | Hunterdon | June 24, 1996 |
| Jesse Eichlin | 81 | Hunterdon | July 10, 1996 |
| Eleanor Stoecker | 60 | Somerset | February 12, 2003 |
| Joyce E. Mangini | 74 | Somerset | February 23, 2003 |
| Giacomino J. Toto | 89 | Somerset | February 23, 2003 |
| John J. Shanagher | 83 | Somerset | March 11, 2003 |
| Dorthea K. Hoagland | 80 | Somerset | April 6, 2003 |
| Melvin T. Simcoe | 66 | Somerset | May 5, 2003 |
| Michael T. Strenko | 21 | Somerset | May 15, 2003 |
| Florian J. Gall | 68 | Somerset | June 28, 2003 |
| Pasquale M. Napolitano | 80 | Somerset | July 13, 2003 |
| Christopher B. Hardgrove | 38 | Somerset | August 11, 2003 |
| Krishnakant Upadhyay | 70 | Somerset | September 20, 2003 |
| James R. Strickland | 83 | Somerset | September 23, 2003 |
| Edward P. Zizik | 73 | Somerset | October 21, 2003 |
| Name | Age | Hospital | Date of Death |
|---|---|---|---|
| Ottomar Schramm | 78 | Easton | December 30, 1998 |
| Matthew Mattern | 22 | Lehigh Valley | August 31, 1999 |
| Irene Krapf | 79 | St. Luke’s | June 22, 2001 |
| William Park | 72 | St. Luke’s | November 8, 2001 |
| Samuel Spangler | 80 | St. Luke’s | January 9, 2002 |
| Daniel George | 82 | St. Luke’s | May 5, 2002 |
| Edward O’Toole | 76 | St. Luke’s | June 2, 2002 |
The average age of Cullen’s confirmed victims was approximately 71 years old, though his youngest victim, Michael Strenko, was just 21 and had been admitted for a routine spleen surgery from which he was expected to fully recover.
Cullen consistently claimed he murdered patients to “spare them from suffering” and prevent them from being “dehumanized” by medical staff during Code Blue emergencies. He told detectives he could not bear to witness or hear about resuscitation attempts on dying patients.
This explanation has been widely discredited for several critical reasons:
While never formally diagnosed during trial, experts have identified several psychological characteristics consistent with Cullen’s behavior:
Major Depression: Cullen had a documented history of severe depression, including approximately 20 suicide attempts throughout his life and multiple psychiatric hospitalizations. He told 60 Minutes: “I tried to kill myself throughout my life because I never really liked being who I was. I didn’t feel I was worthy of anything.”
Antisocial Personality Disorder: His behavior – including lack of remorse, manipulation, and callous disregard for victims’ lives – strongly matches antisocial personality disorder patterns. His ex-wife described bizarre behaviors including torturing the family’s Yorkshire terriers by placing them in trash bins, pouring lighter fluid into drinks, and making prank calls to funeral homes.
Borderline Personality Features:Adrienne Cullen described her ex-husband as having “borderline personality” traits, though this was never clinically confirmed.
Domestic Abuse Pattern:Cullen’s abuse of his family included turning off heat during winter to force his wife and daughter to endure freezing temperatures. His wife filed domestic violence complaints in 1993, though a judge initially dismissed them as “odd behavior, not threatening violence.”
Forensic psychologists categorize healthcare serial killers like Cullen as “angel of death” or “angel of mercy” killers – individuals who murder patients under their care.
Key psychological drivers identified in research:
Notably, unlike typical serial killers with antisocial personality disorder, “angels of death do not always possess antisocial intent. They may believe that their actions eliminate misery and serve the greater good” – making them harder to identify before capture.
Cullen married Adrienne Taub in 1987, and the marriage produced two daughters. The relationship deteriorated rapidly as Cullen’s mental health declined.
Adrienne filed for divorce in January 1993, along with multiple domestic violence complaints. Court documents portrayed Cullen as an alcoholic who engaged in bizarre and cruel behavior. He lost custody of his daughters, receiving only supervised visitation initially, though unsupervised visitation was later granted after the divorce finalized in December 1993.
In March 1993, Cullen broke into the home of Michelle Tomlinson, a nursing colleague, while she and her young son slept. He subsequently began stalking her – making frequent phone calls, leaving messages, and following her at work and around town. He pleaded guilty to trespassing and harassment and received one year of probation.
In May 1998, Cullen filed for bankruptcy, claiming nearly $67,000 in debts. Despite mounting financial problems, court-ordered child support payments forced him to continue working as a nurse – a profession he later claimed he wanted to quit in 1993.
Cullen’s downfall began at Somerset Medical Center, where he killed at least 13 patients in just 13 months. The hospital’s computerized systems revealed troubling patterns:
In July 2003, Dr. Steven Marcus, director of the New Jersey Poison Information and Education System, warned Somerset officials that at least four suspicious overdoses indicated an employee was likely killing patients. The hospital delayed contacting authorities until October 2003, during which time Cullen killed five more patients.
Amy Loughren was a nurse at Somerset who befriended Cullen during their demanding night shifts. He supported her while she dealt with a serious heart condition and cared for her two children when she couldn’t.
When detectives Tim Braun and Danny Baldwin showed Loughren records of Cullen’s suspicious drug withdrawals, she immediately recognized something was wrong. Despite the emotional conflict of betraying a close friend, Loughren agreed to wear a wire during a meeting with Cullen at a bar in Bridgewater, New Jersey.
During their conversation, Cullen made incriminating statements. Loughren later told People magazine: “I was wrestling with how much I still cared for him. He was my friend. I didn’t know the murderer.”
Cullen was arrested at a restaurant on December 12, 2003, and initially charged with one count of murder and one count of attempted murder. Within days, he confessed to detectives that he had killed between 30 and 40 patients over his 16-year career.
In a 2013 60 Minutes interview – the first televised interview with a serial killer in the show’s 45-year history – Cullen acknowledged his crimes while struggling with terminology:
“I think that I had a lot of trouble accepting that word [murder] for a long time. I accept that that’s what it is… I guess it depends upon a person’s definition. If it’s more than one and it’s a pattern, I guess then yeah [I’m a serial killer].”
To avoid the death penalty, Cullen agreed to cooperate with authorities and provide information about his victims. In exchange, prosecutors in all seven counties where he worked agreed not to seek capital punishment.
Guilty Pleas:
On March 2, 2006, Cullen was sentenced to 11 consecutive life terms in New Jersey for 22 murders and 3 attempted murders, making him ineligible for parole for 397 years.
During the hearing, approximately 60 family members of victims confronted Cullen, calling him “vermin,” “garbage,” “trash,” and “an agent from the deepest depths of Hell.” Cullen kept his eyes closed throughout most of the testimony, frustrating grieving relatives who wanted him to look at them.
Richard J. Stoecker, whose mother Eleanor was murdered, said: “In case he forgot what my mother looked like, look into my eyes now.”
At a subsequent Pennsylvania sentencing hearing on March 10, 2006, Cullen repeatedly interrupted proceedings by chanting “Your Honor, you need to step down” for 30 minutes until Judge William Platt ordered him gagged with cloth and duct tape. Even gagged, Cullen continued attempting to repeat the phrase. He received an additional six life sentences in Pennsylvania.
Multiple systemic failures enabled Cullen to kill for 16 years across 10 healthcare facilities:
Inadequate Reporting Requirements: States like New Jersey and Pennsylvania required facilities to report suspicious deaths only in the most egregious cases, with minor penalties for failing to report.
Fear of Litigation: Hospitals feared that investigating incidents or providing negative employment references might trigger lawsuits. As a result, they allowed problematic nurses to quietly resign rather than face termination and reporting.
Nursing Shortage: A nationwide nursing shortage made it difficult for hospitals to thoroughly vet candidates, allowing Cullen to find new employment despite being fired from multiple facilities.
Lack of Information Sharing: No mechanisms existed to identify nurses with mental health issues or employment problems across different facilities. Somerset Medical Center stated: “Mr. Cullen worked at nine other health care facilities over a 16-year period. His former work history problems were not revealed to us.”
Delayed Action: Even when suspicions arose, hospitals often conducted internal investigations before alerting authorities. Somerset Medical Center waited from July to October 2003 to contact police – during which Cullen killed five more patients.
Following Cullen’s arrest, Pennsylvania, New Jersey, and 35 other states adopted new laws designed to prevent similar cases:
However, nearly 20 years later, the Cullen Laws face criticism for harming nurses rather than preventing killers. Critics argue the laws target nurses for minor medication errors while the hospitals that covered up Cullen’s crimes have yet to be held accountable.
Amy Loughren herself has stated: “The Cullen Law was a knee jerk reaction to an incredibly complicated issue which involved hospital negligence. Nurses cannot continue to pay the price for organizations’ errors. Real changes need to be made to this law including the criteria for which a nurse can be reported. The law’s heart was in the right place. However, it’s the individuals who covered up Charles’ crimes that have yet to be held responsible.”
Charles Cullen is currently incarcerated in protective custody at New Jersey State Prison in Trenton, serving 18 consecutive life sentences (11 in New Jersey, 7 in Pennsylvania). According to the Department of Corrections, his earliest possible parole date is June 10, 2388.
In 2005, Cullen requested to donate a kidney to a relative of an ex-girlfriend, and in March 2006, a New Jersey judge agreed to allow the transplant.
Cullen’s crimes have been documented in several books and films:
Charles Cullen’s case illustrates several important patterns in understanding medical serial killers:
The “Angel of Death” archetype represents a distinct category of serial killer who uses their trusted caregiving position to murder vulnerable patients, often claiming mercy as a motive while actually deriving power and control from determining life and death.
Childhood trauma and isolation appear as significant risk factors – Cullen’s early father loss, mother’s death, severe bullying, social isolation, and repeated suicide attempts created a profoundly damaged psychological foundation.
The organized killer profile allowed Cullen to systematically exploit gaps in hospital systems, pharmacy tracking, and inter-facility communication for nearly two decades.
Systemic failures enabled his killing spree as much as his psychological pathology – hospitals repeatedly prioritized avoiding litigation over patient safety, allowing a known problem employee to continue moving through the healthcare system.
Borderline Personality Features: Adrienne Cullen described her ex-husband as having “borderline personality” traits, though this was never clinically confirmed.
Domestic Abuse Pattern: Cullen’s abuse of his family included turning off heat during winter to force his wife and daughter to endure freezing temperatures. His wife filed domestic violence complaints in 1993, though a judge initially dismissed them as “odd behavior, not threatening violence.”
Cullen married Adrienne Taub in 1987, and the marriage produced two daughters. The relationship deteriorated rapidly as Cullen’s mental health declined.
Adrienne filed for divorce in January 1993, along with multiple domestic violence complaints. Court documents portrayed Cullen as an alcoholic who engaged in bizarre and cruel behavior. He lost custody of his daughters, receiving only supervised visitation initially, though unsupervised visitation was later granted after the divorce finalized in December 1993.
In March 1993, Cullen broke into the home of Michelle Tomlinson, a nursing colleague, while she and her young son slept. He subsequently began stalking her – making frequent phone calls, leaving messages, and following her at work and around town. He pleaded guilty to trespassing and harassment and received one year of probation.
In May 1998, Cullen filed for bankruptcy, claiming nearly $67,000 in debts. Despite mounting financial problems, court-ordered child support payments forced him to continue working as a nurse – a profession he later claimed he wanted to quit in 1993.
Cullen’s downfall began at Somerset Medical Center, where he killed at least 13 patients in just 13 months. The hospital’s computerized systems revealed troubling patterns:
In July 2003, Dr. Steven Marcus, director of the New Jersey Poison Information and Education System, warned Somerset officials that at least four suspicious overdoses indicated an employee was likely killing patients. The hospital delayed contacting authorities until October 2003, during which time Cullen killed five more patients.
Amy Loughren was a nurse at Somerset who befriended Cullen during their demanding night shifts. He supported her while she dealt with a serious heart condition and cared for her two children when she couldn’t.
When detectives Tim Braun and Danny Baldwin showed Loughren records of Cullen’s suspicious drug withdrawals, she immediately recognized something was wrong. Despite the emotional conflict of betraying a close friend, Loughren agreed to wear a wire during a meeting with Cullen at a bar in Bridgewater, New Jersey.
During their conversation, Cullen made incriminating statements. Loughren later told People magazine: “I was wrestling with how much I still cared for him. He was my friend. I didn’t know the murderer.”
Cullen was arrested at a restaurant on December 12, 2003, and initially charged with one count of murder and one count of attempted murder. Within days, he confessed to detectives that he had killed between 30 and 40 patients over his 16-year career.
In a 2013 60 Minutes interview – the first televised interview with a serial killer in the show’s 45-year history – Cullen acknowledged his crimes while struggling with terminology:
“I think that I had a lot of trouble accepting that word [murder] for a long time. I accept that that’s what it is… I guess it depends upon a person’s definition. If it’s more than one and it’s a pattern, I guess then yeah [I’m a serial killer].”
To avoid the death penalty, Cullen agreed to cooperate with authorities and provide information about his victims. In exchange, prosecutors in all seven counties where he worked agreed not to seek capital punishment.
Guilty Pleas:
On March 2, 2006, Cullen was sentenced to 11 consecutive life terms in New Jersey for 22 murders and 3 attempted murders, making him ineligible for parole for 397 years.
During the hearing, approximately 60 family members of victims confronted Cullen, calling him “vermin,” “garbage,” “trash,” and “an agent from the deepest depths of Hell.” Cullen kept his eyes closed throughout most of the testimony, frustrating grieving relatives who wanted him to look at them.
Richard J. Stoecker, whose mother Eleanor was murdered, said: “In case he forgot what my mother looked like, look into my eyes now.”
At a subsequent Pennsylvania sentencing hearing on March 10, 2006, Cullen repeatedly interrupted proceedings by chanting “Your Honor, you need to step down” for 30 minutes until Judge William Platt ordered him gagged with cloth and duct tape. Even gagged, Cullen continued attempting to repeat the phrase. He received an additional six life sentences in Pennsylvania.
Multiple systemic failures enabled Cullen to kill for 16 years across 10 healthcare facilities:
Inadequate Reporting Requirements: States like New Jersey and Pennsylvania required facilities to report suspicious deaths only in the most egregious cases, with minor penalties for failing to report.
Fear of Litigation: Hospitals feared that investigating incidents or providing negative employment references might trigger lawsuits. As a result, they allowed problematic nurses to quietly resign rather than face termination and reporting.
Nursing Shortage: A nationwide nursing shortage made it difficult for hospitals to thoroughly vet candidates, allowing Cullen to find new employment despite being fired from multiple facilities.
Lack of Information Sharing: No mechanisms existed to identify nurses with mental health issues or employment problems across different facilities. Somerset Medical Center stated: “Mr. Cullen worked at nine other health care facilities over a 16-year period. His former work history problems were not revealed to us.”
Delayed Action: Even when suspicions arose, hospitals often conducted internal investigations before alerting authorities. Somerset Medical Center waited from July to October 2003 to contact police – during which Cullen killed five more patients.
Following Cullen’s arrest, Pennsylvania, New Jersey, and 35 other states adopted new laws designed to prevent similar cases:
However, nearly 20 years later, the Cullen Laws face criticism for harming nurses rather than preventing killers. Critics argue the laws target nurses for minor medication errors while the hospitals that covered up Cullen’s crimes have yet to be held accountable.
Amy Loughren herself has stated: “The Cullen Law was a knee jerk reaction to an incredibly complicated issue which involved hospital negligence. Nurses cannot continue to pay the price for organizations’ errors. Real changes need to be made to this law including the criteria for which a nurse can be reported. The law’s heart was in the right place. However, it’s the individuals who covered up Charles’ crimes that have yet to be held responsible.”
Charles Cullen is currently incarcerated in protective custody at New Jersey State Prison in Trenton, serving 18 consecutive life sentences (11 in New Jersey, 7 in Pennsylvania). According to the Department of Corrections, his earliest possible parole date is June 10, 2388.
In 2005, Cullen requested to donate a kidney to a relative of an ex-girlfriend, and in March 2006, a New Jersey judge agreed to allow the transplant.
Cullen’s crimes have been documented in several books and films:
Charles Cullen’s case illustrates several important patterns in understanding medical serial killers:
The “Angel of Death” archetype represents a distinct category of serial killer who uses their trusted caregiving position to murder vulnerable patients, often claiming mercy as a motive while actually deriving power and control from determining life and death.
Childhood trauma and isolation appear as significant risk factors – Cullen’s early father loss, mother’s death, severe bullying, social isolation, and repeated suicide attempts created a profoundly damaged psychological foundation.
The organized killer profile allowed Cullen to systematically exploit gaps in hospital systems, pharmacy tracking, and inter-facility communication for nearly two decades.
Systemic failures enabled his killing spree as much as his psychological pathology – hospitals repeatedly prioritized avoiding litigation over patient safety, allowing a known problem employee to continue moving through the healthcare system.

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